Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Cell
organelle |
| gptkbp:abnormalitiesAssociatedWith |
gptkb:cancer
infectious diseases neurodegenerative diseases |
| gptkbp:biogenesisRegulatedBy |
gptkb:mTOR_pathway
ULK1 complex |
| gptkbp:contains |
damaged organelles
protein aggregates cytoplasmic components |
| gptkbp:degradedBy |
lysosomal hydrolases
|
| gptkbp:discoveredBy |
gptkb:Christian_de_Duve
|
| gptkbp:formedBy |
phagophore expansion
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
deliver material to lysosomes
sequester cytoplasmic material |
| gptkbp:fuseWith |
lysosomes
|
| https://www.w3.org/2000/01/rdf-schema#label |
autophagosomes
|
| gptkbp:involvedIn |
autophagy
|
| gptkbp:markerProtein |
gptkb:LC3
Atg8 |
| gptkbp:membraneType |
double-membrane
|
| gptkbp:relatedTo |
gptkb:lysosome
autolysosome phagophore |
| gptkbp:role |
cellular homeostasis
defense against pathogens removal of damaged organelles response to starvation |
| gptkbp:bfsParent |
gptkb:PI3-kinase_Vps34
gptkb:PI3KC3 |
| gptkbp:bfsLayer |
7
|