Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:affects |
lipid metabolism
|
| gptkbp:aminoAcidAtPosition112 |
arginine
|
| gptkbp:aminoAcidAtPosition158 |
arginine
|
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:distinctFrom |
gptkb:apolipoprotein_E2
gptkb:apolipoprotein_E3 |
| gptkbp:encodedBy |
gptkb:APOE_gene
|
| gptkbp:foundIn |
humans
|
| gptkbp:frequency |
~14% worldwide
|
| gptkbp:hasIsoform |
gptkb:apolipoprotein_E
|
| https://www.w3.org/2000/01/rdf-schema#label |
apolipoprotein E4
|
| gptkbp:impact |
neuronal repair
amyloid-beta aggregation cholesterol transport |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
|
| gptkbp:riskFactor |
gptkb:cardiovascular_disease
gptkb:late-onset_Alzheimer's_disease cognitive decline |
| gptkbp:structure |
299 amino acids
|
| gptkbp:bfsParent |
gptkb:APOE_ε4_allele
gptkb:apolipoprotein_E2 |
| gptkbp:bfsLayer |
7
|