Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
serpin |
| gptkbp:alternativeName |
gptkb:A1AT
gptkb:alpha-1_antitrypsin |
| gptkbp:containsGene |
gptkb:SERPINA1
|
| gptkbp:deficiencyCauses |
gptkb:liver_disease
emphysema |
| gptkbp:discoveredBy |
Laurell and Eriksson
|
| gptkbp:discoveredIn |
1963
|
| gptkbp:EC_number |
3.4.21.68
|
| gptkbp:foundIn |
human blood plasma
|
| gptkbp:hasPolymorphism |
gptkb:PiS
PiM PiZ |
| https://www.w3.org/2000/01/rdf-schema#label |
alpha1-proteinase inhibitor
|
| gptkbp:inhibitedBy |
gptkb:trypsin
chymotrypsin neutrophil elastase |
| gptkbp:isAcutePhaseProtein |
true
|
| gptkbp:isGlycosylated |
true
|
| gptkbp:locatedOnChromosome |
14q32.13
|
| gptkbp:medicalUse |
augmentation therapy
|
| gptkbp:molecularWeight |
52 kDa
|
| gptkbp:OMIM |
107400
|
| gptkbp:PDB |
1QLP
|
| gptkbp:producedBy |
liver
|
| gptkbp:structure |
gptkb:protein
|
| gptkbp:UniProtID |
P01009
|
| gptkbp:bfsParent |
gptkb:Alpha-1_antitrypsin
|
| gptkbp:bfsLayer |
8
|