Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:IDUA
gptkb:L-iduronidase |
| gptkbp:biologicalProcess |
glycosaminoglycan degradation
|
| gptkbp:CASNumber |
37278-88-3
|
| gptkbp:deficiencyCauses |
gptkb:Hurler-Scheie_syndrome
gptkb:Hurler_syndrome gptkb:Scheie_syndrome |
| gptkbp:discoveredBy |
1970s
|
| gptkbp:EC_number |
3.2.1.76
|
| gptkbp:enzymeClassification |
gptkb:glycosidase
|
| gptkbp:function |
hydrolyzes terminal alpha-L-iduronic acid residues
|
| gptkbp:gene |
gptkb:IDUA
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-L-iduronidase
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4p16.3
|
| gptkbp:location |
gptkb:lysosome
|
| gptkbp:molecularWeight |
83 kDa
|
| gptkbp:OMIM |
252800
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:substrate |
dermatan sulfate
heparan sulfate |
| gptkbp:UniProtID |
P35475
|
| gptkbp:used_in_therapy |
gptkb:laronidase
|
| gptkbp:bfsParent |
gptkb:mucopolysaccharidosis_type_I_(MPS_I)
|
| gptkbp:bfsLayer |
5
|