Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:activatedBy |
gptkb:Gs_protein
|
| gptkbp:affects |
inflammation
motor control sleep regulation |
| gptkbp:binds |
gptkb:adenosine
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
ADORA2A gene
|
| gptkbp:enemyOf |
gptkb:regadenoson
gptkb:theophylline caffeine CGS-21680 istradefylline |
| gptkbp:expressedIn |
brain
heart immune cells |
| gptkbp:formsHeterodimerWith |
dopamine D2 receptor
|
| https://www.w3.org/2000/01/rdf-schema#label |
adenosine A2A receptor
|
| gptkbp:improves |
cAMP production
|
| gptkbp:involvedIn |
neurotransmission
immune response modulation vasodilation |
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
22q11.23
|
| gptkbp:memberOf |
adenosine receptor family
|
| gptkbp:modulatedBy |
dopamine signaling
|
| gptkbp:OMIM |
102776
|
| gptkbp:PDB |
3EML
|
| gptkbp:target |
Parkinson's disease drugs
|
| gptkbp:UniProtID |
P29274
|
| gptkbp:bfsParent |
gptkb:CHEMBL1173605
gptkb:ADORA2A |
| gptkbp:bfsLayer |
7
|