acid-labile subunit (ALS)

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:IGFALS
Insulin-like growth factor-binding protein complex acid-labile subunit
gptkbp:binds gptkb:IGF-2
gptkb:IGF-1
IGF-binding protein (IGFBP)-3
IGF-binding protein (IGFBP)-5
gptkbp:component insulin-like growth factor (IGF) complex
gptkbp:encodedBy IGFALS gene
gptkbp:foundIn gptkb:human
other mammals
gptkbp:function prolongs half-life of IGFs in circulation
https://www.w3.org/2000/01/rdf-schema#label acid-labile subunit (ALS)
gptkbp:locatedOnChromosome 16p13.3
gptkbp:location gptkb:plasma
gptkbp:molecularWeight ~85 kDa
gptkbp:mutationAssociatedWith growth retardation
gptkbp:OMIM 601489
gptkbp:regulates recombinant human growth hormone
gptkbp:synthesisType liver
gptkbp:UniProtID P35858
gptkbp:bfsParent gptkb:IGFBP3
gptkbp:bfsLayer 7