|
gptkbp:instanceOf
|
antiretroviral therapy
protease inhibitor
|
|
gptkbp:administeredBy
|
oral
intravenous
|
|
gptkbp:approvalYear
|
1987
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J05AF01
|
|
gptkbp:brand
|
gptkb:Retrovir
|
|
gptkbp:CASNumber
|
30516-87-1
|
|
gptkbp:chemicalClass
|
gptkb:zidovudine
|
|
gptkbp:chemicalFormula
|
C10H13N5O4
|
|
gptkbp:combines
|
gptkb:abacavir
gptkb:lamivudine
gptkb:lopinavir/ritonavir
|
|
gptkbp:contraindication
|
hypersensitivity to zidovudine
severe anemia
|
|
gptkbp:developedBy
|
HIV/AIDS treatment
|
|
gptkbp:discoveredBy
|
gptkb:Jerome_Horwitz
|
|
gptkbp:discoveredIn
|
1964
|
|
gptkbp:eliminatedIn
|
urine
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:firstAntiretroviralApproved
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AZT
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits reverse transcriptase
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
267.24 g/mol
|
|
gptkbp:origin
|
originally developed as a potential cancer drug
|
|
gptkbp:patentExpired
|
2005
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:sideEffect
|
gptkb:anemia
nausea
headache
neutropenia
|
|
gptkbp:synonym
|
gptkb:3'-azido-3'-deoxythymidine
gptkb:ZDV
|
|
gptkbp:usedFor
|
HIV infection
post-exposure prophylaxis
prevention of mother-to-child HIV transmission
|
|
gptkbp:bfsParent
|
gptkb:Baku
gptkb:Aghdam
gptkb:Shamakhi
gptkb:Fuzuli_District_(Azerbaijan)
gptkb:Khizi,_Azerbaijan
gptkb:Nakhchivan,_Azerbaijan_SSR,_Soviet_Union
gptkb:Агдам
gptkb:Агдере
gptkb:Балакен
gptkb:Барда
gptkb:Билясувар
gptkb:Гедабек
gptkb:Гобустан
gptkb:Гёйчай
gptkb:Дашкесан
gptkb:Джалилабад
gptkb:Джебраил
gptkb:Загатала
gptkb:Зангилан
gptkb:Зардаб
gptkb:Имышлы
gptkb:Исмаиллы
gptkb:Кельбаджар
gptkb:Кюрдамир
gptkb:Лачин
gptkb:Лерик
gptkb:Масаллы
gptkb:Мингечаур
gptkb:Ордубад
gptkb:Сабирабад
gptkb:Садарак
gptkb:Сальян
gptkb:Сумгаит
gptkb:Тертер
gptkb:Товуз
gptkb:Уджары
gptkb:Хачмаз
gptkb:Ходжавенд
gptkb:Хызы
gptkb:Шабран
gptkb:Шамкир
gptkb:Шарур
gptkb:Шахбуз
gptkb:Шеки
gptkb:Ярдымлы
gptkb:Salyan_District
gptkb:Narimanov_District,_Baku
gptkb:Central_Economic_Region
gptkb:Ganja
gptkb:Mingachevir
gptkb:Nakhchivan
gptkb:Pirallahi_Island
gptkb:Republic_of_Azerbaijan
gptkb:Sumqayit
gptkb:גנג'ה
gptkb:מינגצ'אוויר
gptkb:סומגאיט
gptkb:Tafinlar
gptkb:Aghdam_District
gptkb:Gazakh_District
gptkb:Khojavend_District
gptkb:Shamkir,_Azerbaijan
|
|
gptkbp:bfsLayer
|
5
|