|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
melanoma
osteosarcoma
rheumatoid arthritis
|
|
gptkbp:binds
|
gptkb:Frizzled_receptors
gptkb:ROR2_receptor
gptkb:RYK_receptor
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
gptkb:WNT5A_gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000114251
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
brain
heart
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
Wnt-protein binding
|
|
gptkbp:GOProcess
|
regulation of cell migration
planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
|
|
gptkbp:hasAminoAcidLength
|
380
|
|
gptkbp:hasRefSeqID
|
NP_003384.1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt-5a protein
|
|
gptkbp:involvedIn
|
embryonic development
cancer progression
cell migration
cell polarity
non-canonical Wnt signaling pathway
|
|
gptkbp:locatedOnChromosome
|
3p14.3
|
|
gptkbp:memberOf
|
Wnt protein family
|
|
gptkbp:molecularWeight
|
42 kDa
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Gallus_gallus
gptkb:Mus_musculus
|
|
gptkbp:PDB
|
gptkb:7A1V
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
|
|
gptkbp:subcellularLocation
|
extracellular space
secreted
|
|
gptkbp:UniProtID
|
P41221
|
|
gptkbp:bfsParent
|
gptkb:WNT5A
|
|
gptkbp:bfsLayer
|
7
|