Vascular endothelial growth factor B

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:abbreviation	gptkb:VEGF-B
gptkbp:alternativeSplicing	produces two isoforms
gptkbp:associatedWith	gptkb:cancer gptkb:diabetes gptkb:myocardial_ischemia
gptkbp:binds	gptkb:VEGFR-1 neuropilin-1
gptkbp:discoveredIn	1996
gptkbp:encodedBy	VEGFB gene
gptkbp:Entrez_Gene_ID	7423 ENSG00000173511
gptkbp:expressedIn	gptkb:brown_adipose_tissue gptkb:skeletal_muscle brain heart
gptkbp:foundIn	humans mice
gptkbp:function	regulation of angiogenesis regulation of endothelial cell function
gptkbp:hasIsoform	gptkb:VEGF-B167 gptkb:VEGF-B186
gptkbp:HGNC_ID	12697
gptkbp:locatedOnChromosome	chromosome 11q13 (human)
gptkbp:memberOf	gptkb:vascular_endothelial_growth_factor_family
gptkbp:molecularWeight	~21 kDa
gptkbp:OMIM	601121
gptkbp:PDB	2VGH
gptkbp:RefSeq	NM_003377
gptkbp:role	cardiovascular system neuroprotection metabolic regulation
gptkbp:structure	homodimer
gptkbp:UniProtID	gptkb:P49765
gptkbp:bfsParent	gptkb:VEGF-B
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Vascular endothelial growth factor B