Vascular endothelial growth factor B

URI: https://gptkb.org/entity/Vascular_endothelial_growth_factor_B
GPTKB entity
Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:VEGF-B
gptkbp:alternativeSplicing produces two isoforms
gptkbp:associatedWith gptkb:cancer
gptkb:diabetes
gptkb:myocardial_ischemia
gptkbp:binds gptkb:VEGFR-1
neuropilin-1
gptkbp:discoveredIn 1996
gptkbp:encodedBy VEGFB gene
gptkbp:Entrez_Gene_ID 7423
ENSG00000173511
gptkbp:expressedIn gptkb:brown_adipose_tissue
gptkb:skeletal_muscle
brain
heart
gptkbp:foundIn humans
mice
gptkbp:function regulation of angiogenesis
regulation of endothelial cell function
gptkbp:hasIsoform gptkb:VEGF-B167
gptkb:VEGF-B186
gptkbp:HGNC_ID 12697
https://www.w3.org/2000/01/rdf-schema#label Vascular endothelial growth factor B
gptkbp:locatedOnChromosome chromosome 11q13 (human)
gptkbp:memberOf gptkb:vascular_endothelial_growth_factor_family
gptkbp:molecularWeight ~21 kDa
gptkbp:OMIM 601121
gptkbp:PDB 2VGH
gptkbp:RefSeq NM_003377
gptkbp:role cardiovascular system
neuroprotection
metabolic regulation
gptkbp:structure homodimer
gptkbp:UniProtID gptkb:P49765
gptkbp:bfsParent gptkb:VEGF-B
gptkbp:bfsLayer 7