|
gptkbp:instanceOf
|
gptkb:antibiotic
glycopeptide antibiotic
|
|
gptkbp:administeredBy
|
gptkb:pneumonia
meningitis
septicemia
peritonitis
endocarditis
osteomyelitis
inflammatory bowel disease
bacteremia
skin and soft tissue infections
septic arthritis
infections caused by coagulase-negative staphylococci
infections caused by Bacillus species
infections caused by Corynebacterium species
infections caused by Enterococcus species
infections caused by Listeria monocytogenes
infections caused by Streptococcus species
prosthetic joint infections
severe infections in penicillin-allergic patients
ventriculitis
|
|
gptkbp:approvedBy
|
1958
|
|
gptkbp:ATCCode
|
J01XA01
|
|
gptkbp:brand
|
gptkb:Vancocin
|
|
gptkbp:CASNumber
|
1404-93-9
|
|
gptkbp:contraindication
|
hypersensitivity to vancomycin
|
|
gptkbp:discoveredBy
|
gptkb:Edmund_Kornfeld
|
|
gptkbp:discoveredIn
|
1953
|
|
gptkbp:drugInteraction
|
gptkb:loop_diuretics
gptkb:aminoglycosides
|
|
gptkbp:eliminationHalfLife
|
4–8 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C66H75Cl2N9O24
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Vancomycin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits cell wall synthesis
|
|
gptkbp:notAbsorbedOrally
|
true
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:producedBy
|
gptkb:Amycolatopsis_orientalis
|
|
gptkbp:resistantTo
|
gptkb:vancomycin-intermediate_Staphylococcus_aureus_(VISA)
gptkb:vancomycin-resistant_enterococci_(VRE)
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
gptkb:red_man_syndrome
nephrotoxicity
ototoxicity
|
|
gptkbp:usedFor
|
gptkb:methicillin-resistant_Staphylococcus_aureus_(MRSA)
gptkb:Clostridioides_difficile_infection
treatment of serious Gram-positive infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Antibiotics
|
|
gptkbp:bfsLayer
|
4
|