Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:antibiotic
|
gptkbp:administeredBy |
intramuscular
intravenous |
gptkbp:chemicalFormula |
amino sugars linked by glycosidic bonds
|
gptkbp:contraindication |
gptkb:myasthenia_gravis
pregnancy |
gptkbp:discoveredIn |
1940s
|
gptkbp:eliminatedIn |
renal
|
gptkbp:example |
gptkb:tobramycin
gptkb:neomycin gptkb:amikacin gentamicin streptomycin |
https://www.w3.org/2000/01/rdf-schema#label |
aminoglycosides
|
gptkbp:mechanismOfAction |
inhibit protein synthesis
|
gptkbp:notEffectiveAgainst |
anaerobic bacteria
|
gptkbp:resistantTo |
altered ribosomal binding site
modifying enzymes |
gptkbp:sideEffect |
nephrotoxicity
ototoxicity |
gptkbp:spectrumOfActivity |
gram-negative bacteria
some gram-positive bacteria |
gptkbp:target |
gptkb:30S_ribosomal_subunit
|
gptkbp:usedFor |
bacterial infections
|
gptkbp:WHOStatus |
essential medicines
|
gptkbp:bfsParent |
gptkb:Vancomycin
|
gptkbp:bfsLayer |
5
|