Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:administeredBy |
intramuscular
intravenous |
| gptkbp:chemicalFormula |
amino sugars linked by glycosidic bonds
|
| gptkbp:contraindication |
gptkb:myasthenia_gravis
pregnancy |
| gptkbp:discoveredIn |
1940s
|
| gptkbp:eliminatedIn |
renal
|
| gptkbp:example |
gptkb:tobramycin
gptkb:neomycin gptkb:amikacin gentamicin streptomycin |
| gptkbp:mechanismOfAction |
inhibit protein synthesis
|
| gptkbp:notEffectiveAgainst |
anaerobic bacteria
|
| gptkbp:resistantTo |
altered ribosomal binding site
modifying enzymes |
| gptkbp:sideEffect |
nephrotoxicity
ototoxicity |
| gptkbp:spectrumOfActivity |
gram-negative bacteria
some gram-positive bacteria |
| gptkbp:target |
gptkb:30S_ribosomal_subunit
|
| gptkbp:usedFor |
bacterial infections
|
| gptkbp:WHOStatus |
essential medicines
|
| gptkbp:bfsParent |
gptkb:Pseudomonas_aeruginosa
gptkb:Acinetobacter_baumannii gptkb:Yersinia_pseudotuberculosis |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
aminoglycosides
|