loop diuretics

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf class of medication
gptkbp:ATCCode C03CA
gptkbp:contraindication sulfa allergy (except ethacrynic acid)
gptkbp:discoveredIn 1960s
gptkbp:eliminatedIn renal
gptkbp:example furosemide
bumetanide
ethacrynic acid
torsemide
https://www.w3.org/2000/01/rdf-schema#label loop diuretics
gptkbp:mechanismOfAction inhibit sodium-potassium-chloride cotransporter in thick ascending limb of loop of Henle
gptkbp:pregnancyCategory C (varies by drug)
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect dehydration
hypokalemia
ototoxicity
hypomagnesemia
hyperuricemia
gptkbp:usedFor treatment of hypertension
treatment of edema
gptkbp:bfsParent gptkb:Vancomycin
gptkbp:bfsLayer 5