Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:class_of_medication
|
| gptkbp:ATCCode |
C03CA
|
| gptkbp:contraindication |
sulfa allergy (except ethacrynic acid)
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:eliminatedIn |
renal
|
| gptkbp:example |
furosemide
bumetanide ethacrynic acid torsemide |
| gptkbp:mechanismOfAction |
inhibit sodium-potassium-chloride cotransporter in thick ascending limb of loop of Henle
|
| gptkbp:pregnancyCategory |
C (varies by drug)
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
dehydration
hypokalemia ototoxicity hypomagnesemia hyperuricemia |
| gptkbp:usedFor |
treatment of hypertension
treatment of edema |
| gptkbp:bfsParent |
gptkb:loop_of_Henle
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
loop diuretics
|