Clostridioides difficile infection

URI: https://gptkb.org/entity/Clostridioides_difficile_infection
GPTKB entity
Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects gptkb:large_intestine
humans
colon
gptkbp:alsoKnownAs C. diff infection
gptkbp:cause dehydration
electrolyte imbalance
recurrent infection
gptkbp:causedBy gptkb:Clostridioides_difficile
gptkbp:complication gptkb:pseudomembranous_colitis
sepsis
toxic megacolon
gptkbp:diagnosedBy stool test
PCR assay
enzyme immunoassay
gptkbp:firstDescribed 1978
gptkbp:hasEpidemic gptkb:Europe
gptkb:North_America
gptkbp:hasVaccine no approved vaccine as of 2024
https://www.w3.org/2000/01/rdf-schema#label Clostridioides difficile infection
gptkbp:ICD-10_code A04.7
gptkbp:isNotifiableDisease in some countries
gptkbp:meshID D015179
gptkbp:mortalityRate can be high in severe cases
gptkbp:prevalence common in healthcare settings
gptkbp:prevention hand hygiene
antibiotic stewardship
gptkbp:riskFactor antibiotic use
immunosuppression
hospitalization
older age
gptkbp:symptom fever
nausea
diarrhea
abdominal pain
loss of appetite
gptkbp:transmission fecal-oral route
gptkbp:treatment gptkb:metronidazole
gptkb:fidaxomicin
gptkb:fecal_microbiota_transplantation
vancomycin
gptkbp:bfsParent gptkb:Antibiotics
gptkbp:bfsLayer 4