|
gptkbp:instanceOf
|
gptkb:virus
|
|
gptkbp:antigenicProperties
|
cross-protective against orthopoxviruses
|
|
gptkbp:antiviralTreatment
|
gptkb:tecovirimat
gptkb:brincidofovir
gptkb:cidofovir
|
|
gptkbp:associatedWith
|
gptkb:vaccinia
|
|
gptkbp:biosafetyLevel
|
gptkb:BSL-2
|
|
gptkbp:discoveredBy
|
gptkb:Edward_Jenner
|
|
gptkbp:distinctFrom
|
gptkb:variola_virus
gptkb:cowpox_virus
gptkb:monkeypox_virus
|
|
gptkbp:entryMechanism
|
fusion with plasma membrane
|
|
gptkbp:enveloped
|
true
|
|
gptkbp:family
|
gptkb:Poxviridae
|
|
gptkbp:firstDescribed
|
18th century
|
|
gptkbp:genomeSize
|
~190 kbp
|
|
gptkbp:genomeType
|
double-stranded DNA
|
|
gptkbp:genus
|
gptkb:Orthopoxvirus
|
|
gptkbp:hostedBy
|
gptkb:livestock
humans
other mammals
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Vaccinia virus
|
|
gptkbp:proteinCodingGenes
|
~200
|
|
gptkbp:relatedTo
|
gptkb:variola_virus
gptkb:cowpox_virus
gptkb:monkeypox_virus
|
|
gptkbp:replicationCycle
|
cytoplasmic
|
|
gptkbp:replicationSite
|
gptkb:cytoplasm
|
|
gptkbp:shape
|
brick-shaped
|
|
gptkbp:size
|
about 360 x 270 x 250 nm
|
|
gptkbp:structure
|
linear DNA genome
|
|
gptkbp:transmission
|
direct contact
inoculation
|
|
gptkbp:usedFor
|
smallpox vaccine
|
|
gptkbp:usedIn
|
gptkb:biotechnology
immunology research
gene delivery
oncolytic virus therapy
recombinant vaccine development
viral vector development
|
|
gptkbp:vaccineComplications
|
gptkb:eczema_vaccinatum
gptkb:generalized_vaccinia
gptkb:postvaccinal_encephalitis
gptkb:progressive_vaccinia
|
|
gptkbp:vaccineStrain
|
gptkb:ACAM2000
gptkb:Dryvax
gptkb:Lister_strain
|
|
gptkbp:vaccineType
|
live attenuated
|
|
gptkbp:WHOStatus
|
used in eradication of smallpox
|
|
gptkbp:bfsParent
|
gptkb:C6L
gptkb:Orthopoxvirus
gptkb:Poxviridae
|
|
gptkbp:bfsLayer
|
5
|