gptkbp:instanceOf
|
antiviral drug
|
gptkbp:approvedBy
|
gptkb:European_Union
gptkb:United_States
gptkb:FDA
2018
|
gptkbp:ATCCode
|
J05AX25
|
gptkbp:brand
|
gptkb:TPOXX
gptkb:Tpoxx
|
gptkbp:CASNumber
|
869572-92-9
|
gptkbp:chemicalFormula
|
C19H15F3N2O3
|
gptkbp:developedBy
|
gptkb:SIGA_Technologies
|
gptkbp:hasSMILES
|
C1=CC(=CC=C1C2=NC(=O)C(=C(N2)C3=CC=C(C=C3)C(F)(F)F)O)O
|
https://www.w3.org/2000/01/rdf-schema#label
|
tecovirimat
|
gptkbp:KEGGID
|
D10541
|
gptkbp:legalStatus
|
prescription only
|
gptkbp:mechanismOfAction
|
inhibits orthopoxvirus VP37 envelope wrapping protein
|
gptkbp:molecularWeight
|
376.33 g/mol
|
gptkbp:pregnancyCategory
|
Not assigned (US)
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL2103837
25154825
DB12020
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
gptkbp:sideEffect
|
nausea
vomiting
diarrhea
abdominal pain
headache
|
gptkbp:UNII
|
6L6X2DWN5V
|
gptkbp:usedFor
|
treatment of cowpox
treatment of monkeypox
treatment of orthopoxvirus infections
treatment of smallpox
|
gptkbp:bfsParent
|
gptkb:Vaccinia_virus
gptkb:Siga_Technologies
|
gptkbp:bfsLayer
|
6
|