variola virus

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:Baltimore_classification Group I (dsDNA viruses)
gptkbp:biosafetyLevel BSL-4
gptkbp:category bioterrorism agent
select agent
gptkbp:cause gptkb:smallpox
gptkbp:discoveredBy gptkb:Edward_Jenner
gptkbp:enveloped yes
gptkbp:eradicated yes
gptkbp:eradicationYear 1980
gptkbp:family gptkb:Poxviridae
gptkbp:firstDescribed 18th century
gptkbp:genomeSize ~186 kbp
gptkbp:genomeType double-stranded DNA
gptkbp:genus gptkb:Orthopoxvirus
gptkbp:hostedBy gptkb:human
https://www.w3.org/2000/01/rdf-schema#label variola virus
gptkbp:ICTVdB 00.058.0.01.001
gptkbp:incubationPeriod 7-17 days
gptkbp:mortalityRate <1% (Variola minor)
up to 30% (Variola major)
gptkbp:notableOutbreaks gptkb:20th_century_India
18th century Europe
gptkbp:notableStrain gptkb:Variola_major
gptkb:Variola_minor
gptkbp:officialEradicationDeclaration gptkb:World_Health_Organization,_1980
gptkbp:order gptkb:Chitovirales
gptkbp:relatedTo gptkb:vaccinia_virus
gptkb:cowpox_virus
gptkb:monkeypox_virus
gptkbp:replicationSite gptkb:cytoplasm
gptkbp:reservoirName gptkb:human
gptkbp:shape brick-shaped
gptkbp:storage gptkb:CDC,_USA
gptkb:VECTOR,_Russia
gptkbp:symptom fever
rash
pustules
gptkbp:taxonRank gptkb:species
gptkbp:transmission human-to-human
gptkbp:transmissionRoute direct contact
respiratory droplets
fomites
gptkbp:vaccineAvailable yes
gptkbp:vaccineType live attenuated (vaccinia virus)
gptkbp:WHOReferenceLab gptkb:State_Research_Center_of_Virology_and_Biotechnology_VECTOR
gptkb:Centers_for_Disease_Control_and_Prevention_(CDC)
gptkbp:bfsParent gptkb:smallpox
gptkbp:bfsLayer 5