Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:advocacy |
required prior to administration
|
| gptkbp:approves |
gptkb:2001
gptkb:FDA |
| gptkbp:average_temperature |
2 to 8 degrees Celsius
|
| gptkbp:clinical_trial |
Phase III trials
|
| gptkbp:clinical_use |
bioterrorism preparedness
|
| gptkbp:contains |
vaccinia virus
|
| gptkbp:contraindication |
immunocompromised individuals
specific contraindications outlined by CDC |
| gptkbp:developed_by |
gptkb:Sanofi_Pasteur
|
| gptkbp:dosage_form |
lyophilized powder
|
| https://www.w3.org/2000/01/rdf-schema#label |
ACAM2000
|
| gptkbp:indication |
post-exposure prophylaxis for smallpox
|
| gptkbp:ingredients |
live vaccinia virus
|
| gptkbp:invention |
patented
|
| gptkbp:is_recommended_for |
gptkb:military_personnel
healthcare workers |
| gptkbp:is_vulnerable_to |
live attenuated vaccine
requires trained personnel limited to specific populations CDC provides recommendations for use available through the Strategic National Stockpile cost varies by provider developed in response to bioterrorism threats high efficacy against smallpox monitored for safety and efficacy ongoing research for new applications significant impact on public health preparedness |
| gptkbp:manufacturer |
gptkb:United_States
|
| gptkbp:market |
ongoing
|
| gptkbp:marketed_as |
gptkb:ACAM2000
|
| gptkbp:recommissioned |
requires diluent
|
| gptkbp:related_to |
smallpox vaccine
|
| gptkbp:replaces |
Dryvax
|
| gptkbp:route_of_administration |
subcutaneous injection
|
| gptkbp:safety_measures |
conducted by CDC
|
| gptkbp:shelf_life |
36 months
|
| gptkbp:side_effect |
headache
muscle pain fever injection site reactions serious adverse events are rare |
| gptkbp:suitable_for |
pregnant women
people with eczema people with certain skin conditions |
| gptkbp:trade |
gptkb:ACAM2000
|
| gptkbp:type |
live virus vaccine
|
| gptkbp:used_for |
prevention of smallpox
|
| gptkbp:vaccine_documentation |
requires documentation of administration
|
| gptkbp:vaccine_regulation |
regulated by FDA
|
| gptkbp:vaccine_training |
training required for administration
|