VAV1

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alias gptkb:VAV
VAV oncogene
VAV proto-oncogene 1
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:T-cell_leukemia
autoimmune disorders
gptkbp:domain gptkb:PH_domain
SH2 domain
SH3 domain
DH domain
gptkbp:encodes guanine nucleotide exchange factor Vav1
gptkbp:Entrez_Gene_ID 7409
ENSG00000120963
gptkbp:expressedIn hematopoietic cells
gptkbp:function signal transduction
T-cell development
regulation of cytoskeleton organization
hematopoietic cell signaling
gptkbp:gene gptkb:VAV1
gptkbp:HGNC_ID 12658
https://www.w3.org/2000/01/rdf-schema#label VAV1
gptkbp:locatedOnChromosome 19q13.2
gptkbp:OMIM 164762
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Vav1
gptkbp:phosphorylates tyrosine kinases
gptkbp:UniProtID P15498
gptkbp:bfsParent gptkb:Vav1
gptkb:PLCG2
gptkb:TEC_tyrosine_kinase
gptkbp:bfsLayer 7