Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
collagen |
gptkbp:associatedWith |
gptkb:progressive_systemic_sclerosis
Ehlers-Danlos syndrome osteogenesis imperfecta |
gptkbp:biosynthesisLocation |
fibroblast
osteoblast |
gptkbp:degradedBy |
collagenase
|
gptkbp:encodedBy |
gptkb:COL1A1_gene
gptkb:COL1A2_gene |
gptkbp:foundIn |
gptkb:bone
gptkb:skin gptkb:artery cornea tendon dentin fibrocartilage ligament |
gptkbp:function |
structural support
provides tensile strength |
https://www.w3.org/2000/01/rdf-schema#label |
Type I collagen
|
gptkbp:majorComponentOf |
extracellular matrix
|
gptkbp:molecularWeight |
approximately 300 kDa
|
gptkbp:percentageOfTotalCollagen |
about 90%
|
gptkbp:postTranslationalModification |
glycosylation
hydroxylation |
gptkbp:structure |
triple helix
|
gptkbp:subunit |
one alpha-2 chain
two alpha-1 chains |
gptkbp:bfsParent |
gptkb:collagen
|
gptkbp:bfsLayer |
6
|