progressive systemic sclerosis

URI: https://gptkb.org/entity/progressive_systemic_sclerosis
GPTKB entity
Statements (42)
Predicate Object
gptkbp:instanceOf autoimmune disease
connective tissue disease
gptkbp:abbreviation gptkb:PSS
gptkbp:affects gptkb:skin
heart
lungs
gastrointestinal tract
kidneys
gptkbp:alsoKnownAs gptkb:systemic_sclerosis
gptkbp:associatedWith gptkb:anti-RNA_polymerase_III_antibody
gptkb:anti-centromere_antibody
anti-Scl-70 antibody
gptkbp:cause autoimmune reaction
gptkbp:complication heart failure
renal failure
pulmonary hypertension
gptkbp:diagnosedBy clinical examination
skin biopsy
autoantibody testing
gptkbp:field immunology
rheumatology
gptkbp:firstDescribed gptkb:Carlo_Curzio
1753
https://www.w3.org/2000/01/rdf-schema#label progressive systemic sclerosis
gptkbp:ICD-10_code M34
gptkbp:onset adulthood
gptkbp:prevalence rare
gptkbp:riskFactor family history
female sex
gptkbp:subspecies gptkb:diffuse_cutaneous_systemic_sclerosis
gptkb:limited_cutaneous_systemic_sclerosis
gptkbp:symptom gptkb:Raynaud's_phenomenon
telangiectasia
pulmonary fibrosis
skin thickening
esophageal dysmotility
renal crisis
gptkbp:treatment physical therapy
corticosteroids
immunosuppressive drugs
gptkbp:bfsParent gptkb:Type_I_collagen
gptkbp:bfsLayer 7