Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:application |
gptkb:biotechnology
gptkb:medicine agriculture gene editing genome engineering gene knockout |
| gptkbp:class |
Class 2 CRISPR system
|
| gptkbp:component |
gptkb:CRISPR_array
gptkb:Cas_genes gptkb:crRNA gptkb:tracrRNA |
| gptkbp:discoveredIn |
gptkb:Streptococcus_pyogenes
|
| gptkbp:firstDescribed |
2012
|
| gptkbp:foundIn |
gptkb:Bacteria
|
| gptkbp:function |
adaptive immunity
|
| gptkbp:hasProtein |
gptkb:Cas9
gptkb:Cas1 gptkb:Cas2 Csn2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Type II CRISPR-Cas system
|
| gptkbp:mechanismOfAction |
DNA interference
spacer acquisition crRNA biogenesis target interference |
| gptkbp:notableContributor |
gptkb:Emmanuelle_Charpentier
gptkb:Jennifer_Doudna |
| gptkbp:notableFor |
gptkb:Cas9
|
| gptkbp:requires |
gptkb:tracrRNA
PAM sequence |
| gptkbp:subspecies |
II-A
II-B II-C |
| gptkbp:usedIn |
genome editing
|
| gptkbp:bfsParent |
gptkb:Class_2_CRISPR-Cas_system
gptkb:Type_V_CRISPR-Cas_system |
| gptkbp:bfsLayer |
8
|