Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Mixed-Lineage Leukemia complex
|
| gptkbp:amendedBy |
histone H3 lysine 4 (H3K4)
|
| gptkbp:associatedWith |
leukemia
|
| gptkbp:component |
gptkb:ASH2L
gptkb:DPY30 gptkb:RBBP5 gptkb:WDR5 MLL protein |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:function |
histone methyltransferase activity
|
| gptkbp:gene |
gptkb:KMT2A
|
| https://www.w3.org/2000/01/rdf-schema#label |
MLL complex
|
| gptkbp:interactsWith |
gptkb:CBP/p300
gptkb:MEN1 LEDGF |
| gptkbp:involvedIn |
transcriptional activation
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:mutationAssociatedWith |
gptkb:acute_myeloid_leukemia
leukemia |
| gptkbp:orthologIn |
Drosophila trithorax group
|
| gptkbp:regulates |
HOX gene expression
|
| gptkbp:requires |
embryonic development
hematopoiesis |
| gptkbp:target |
therapeutic inhibitors
|
| gptkbp:bfsParent |
gptkb:Menin
|
| gptkbp:bfsLayer |
7
|