Triose-phosphate isomerase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:activeSiteResidue	Glu165 (human) His95 (human)
gptkbp:associatedWith	gptkb:anemia
gptkbp:catalyzes	interconversion of dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
gptkbp:cofactor	none
gptkbp:deficiencyCauses	gptkb:triosephosphate_isomerase_deficiency
gptkbp:discoveredBy	gptkb:Carl_Neuberg
gptkbp:EC_number	5.3.1.1
gptkbp:enzymeClassification	gptkb:isomerase
gptkbp:foldable	gptkb:TIM_barrel
gptkbp:foundIn	gptkb:gluconeogenesis_pathway gptkb:glycolysis_pathway
gptkbp:gene	gptkb:TPI1
gptkbp:GO_term	gptkb:GO:0004807
gptkbp:inhibitedBy	phosphoenolpyruvate
gptkbp:locatedIn	gptkb:cytoplasm
gptkbp:molecularWeight	~27 kDa
gptkbp:OMIM	190450
gptkbp:PDB	gptkb:1TIM
gptkbp:presentIn	gptkb:Bacteria archaea eukaryotes
gptkbp:product	gptkb:glyceraldehyde_3-phosphate dihydroxyacetone phosphate
gptkbp:requires	energy production
gptkbp:structure	homodimer
gptkbp:substrate	gptkb:glyceraldehyde_3-phosphate dihydroxyacetone phosphate
gptkbp:UniProtID	gptkb:P60174
gptkbp:bfsParent	gptkb:P60174
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	Triose-phosphate isomerase