Transcription Activator-Like Effector Nuclease
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genome editing tool
|
| gptkbp:abbreviation |
gptkb:TALEN
|
| gptkbp:alternativeTo |
gptkb:CRISPR-Cas9
|
| gptkbp:application |
gene knockout
gene correction gene insertion |
| gptkbp:bindingDomainOrigin |
gptkb:Xanthomonas_bacteria
|
| gptkbp:composedOf |
FokI nuclease domain
DNA-binding domain |
| gptkbp:developedBy |
researchers at Iowa State University
|
| gptkbp:firstDescribed |
2010
|
| https://www.w3.org/2000/01/rdf-schema#label |
Transcription Activator-Like Effector Nuclease
|
| gptkbp:mechanismOfAction |
induces double-strand breaks
|
| gptkbp:recognizedBy |
modular DNA recognition code
|
| gptkbp:relatedTo |
gptkb:CRISPR
gptkb:Zinc_finger_nuclease |
| gptkbp:target |
specific DNA sequences
|
| gptkbp:usedFor |
genome editing
|
| gptkbp:usedIn |
animal genome editing
plant genome editing human cell genome editing |
| gptkbp:bfsParent |
gptkb:TALEN
|
| gptkbp:bfsLayer |
6
|