|
gptkbp:instanceOf
|
gptkb:tissue_plasminogen_activator
gptkb:drug
|
|
gptkbp:administeredBy
|
single bolus injection
|
|
gptkbp:approvedBy
|
2000
|
|
gptkbp:ATCCode
|
B01AD11
|
|
gptkbp:brand
|
Metalyse
TNKase
|
|
gptkbp:CASNumber
|
177024-62-3
|
|
gptkbp:contraindication
|
active internal bleeding
severe uncontrolled hypertension
history of stroke
|
|
gptkbp:developedBy
|
gptkb:Boehringer_Ingelheim
gptkb:Genentech
|
|
gptkbp:eliminationHalfLife
|
20-24 minutes
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tenecteplase
|
|
gptkbp:indication
|
ST-elevation myocardial infarction
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
gptkb:tissue_plasminogen_activator
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
65 kDa
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:product
|
gptkb:protein
|
|
gptkbp:relatedTo
|
gptkb:alteplase
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
bleeding
allergic reactions
|
|
gptkbp:UNII
|
Q1J8A2JZ4B
|
|
gptkbp:usedFor
|
gptkb:acute_myocardial_infarction
ischemic stroke
|
|
gptkbp:bfsParent
|
gptkb:Thrombolytics
|
|
gptkbp:bfsLayer
|
7
|