|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:administeredBy
|
Healthcare professionals
|
|
gptkbp:alsoKnownAs
|
gptkb:Fibrinolytics
|
|
gptkbp:antidote
|
gptkb:Aminocaproic_acid
gptkb:Tranexamic_acid
|
|
gptkbp:category
|
Antithrombotic agents
|
|
gptkbp:commonHealthIssues
|
gptkb:Alteplase
gptkb:Reteplase
gptkb:Streptokinase
gptkb:Tenecteplase
|
|
gptkbp:compatibleWith
|
Hemorrhagic stroke
|
|
gptkbp:contraindication
|
Active internal bleeding
History of hemorrhagic stroke
Recent major surgery
|
|
gptkbp:discoveredIn
|
20th century
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Thrombolytics
|
|
gptkbp:mechanismOfAction
|
Activate plasminogen
Dissolve blood clots
|
|
gptkbp:monitors
|
Coagulation parameters
|
|
gptkbp:pregnancyCategory
|
C (varies by drug)
|
|
gptkbp:regulates
|
gptkb:FDA
|
|
gptkbp:riskFactor
|
Intracranial hemorrhage
Reperfusion arrhythmias
|
|
gptkbp:routeOfAdministration
|
Intravenous
|
|
gptkbp:sideEffect
|
Allergic reactions
Bleeding
Hypotension
|
|
gptkbp:usedFor
|
gptkb:Acute_myocardial_infarction
Pulmonary embolism
Ischemic stroke
|
|
gptkbp:bfsParent
|
gptkb:Heart_Attack
|
|
gptkbp:bfsLayer
|
6
|