|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:CCT
gptkb:TCP-1_Ring_Complex
|
|
gptkbp:assistsFoldingOf
|
gptkb:actin
tubulin
WD40 repeat proteins
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:ATPDependent
|
true
|
|
gptkbp:composedOf
|
eight different subunits
|
|
gptkbp:discoveredIn
|
1990s
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
gptkbp:function
|
molecular chaperone
|
|
gptkbp:GO_term
|
GO:0005832
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRiC
|
|
gptkbp:involvedIn
|
protein folding
cellular homeostasis
prevention of protein aggregation
|
|
gptkbp:locatedIn
|
cytosol
|
|
gptkbp:molecularWeight
|
~1 MDa
|
|
gptkbp:orthologIn
|
animals
fungi
plants
|
|
gptkbp:PDB
|
4V94
5GW4
6P07
|
|
gptkbp:regulates
|
post-translational modifications
co-chaperones
|
|
gptkbp:relatedTo
|
GroEL (bacterial chaperonin)
|
|
gptkbp:requires
|
cell viability
|
|
gptkbp:reviewedBy
|
GeneCards: CCT Complex
Reactome: R-HSA-390466
UniProt: Q99832
Wikipedia: TRiC
|
|
gptkbp:structure
|
double-ring
|
|
gptkbp:studiedIn
|
gptkb:human
gptkb:mouse
gptkb:yeast
|
|
gptkbp:subunit
|
gptkb:CCT1
gptkb:CCT2
gptkb:CCT3
gptkb:CCT4
gptkb:CCT5
gptkb:CCT6
gptkb:CCT7
gptkb:CCT8
|
|
gptkbp:bfsParent
|
gptkb:CCT_(Complex_of_Chaperonins_Containing_TCP-1)
|
|
gptkbp:bfsLayer
|
7
|