TCP-1 Ring Complex

GPTKB entity

Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CCT
gptkb:TRiC
gptkbp:assistsFoldingOf gptkb:actin
tubulin
other cytosolic proteins
gptkbp:composedOf eight different subunits
gptkbp:discoveredIn 1990s
gptkbp:foundIn eukaryotic cells
gptkbp:function molecular chaperone
gptkbp:gene gptkb:TCP1
CCT genes
https://www.w3.org/2000/01/rdf-schema#label TCP-1 Ring Complex
gptkbp:involves gptkb:cancer
neurodegenerative diseases
protein misfolding diseases
gptkbp:locatedIn cytosol
gptkbp:orthologIn archaeal thermosome
bacterial GroEL
gptkbp:relatedTo protein folding
proteostasis
gptkbp:requires gptkb:ATP
cell viability
gptkbp:structure barrel-shaped
double-ring
gptkbp:studiedIn gptkb:yeast
humans
mammals
gptkbp:subunit gptkb:CCT1
gptkb:CCT2
gptkb:CCT3
gptkb:CCT4
gptkb:CCT5
gptkb:CCT6
gptkb:CCT7
gptkb:CCT8
gptkbp:UniProtID P17987 (TCP1 subunit)
gptkbp:bfsParent gptkb:CCT_(Complex_of_Chaperonins_Containing_TCP-1)
gptkbp:bfsLayer 7