Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alsoKnownAs |
gptkb:CD134
gptkb:OX40 ACT35 |
gptkbp:alternativeSplicing |
yes
|
gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases |
gptkbp:biologicalProcess |
costimulatory immune receptor
|
gptkbp:discoveredIn |
1990s
|
gptkbp:encodes |
OX40 protein
|
gptkbp:Entrez_Gene_ID |
7293
ENSG00000186827 |
gptkbp:expressedIn |
activated T cells
|
gptkbp:fullName |
Tumor necrosis factor receptor superfamily member 4
|
gptkbp:geneType |
protein-coding
|
gptkbp:HGNC_ID |
11935
|
https://www.w3.org/2000/01/rdf-schema#label |
TNFRSF4
|
gptkbp:interactsWith |
TNFSF4
|
gptkbp:locatedOnChromosome |
chromosome 1
1p36.33 |
gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
gptkbp:orthologInMouse |
Tnfrsf4
|
gptkbp:regulates |
cytokine production
T cell proliferation T cell survival |
gptkbp:target |
immunotherapy
|
gptkbp:transmembraneDomains |
present
|
gptkbp:type |
gptkb:MAPK_pathway
gptkb:NF-kappaB_pathway |
gptkbp:UniProtID |
P43489
|
gptkbp:bfsParent |
gptkb:CD134
gptkb:TNFRSF |
gptkbp:bfsLayer |
8
|