Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:CD357
gptkb:GITR AITR |
| gptkbp:associatedWith |
immunotherapy
autoimmune diseases |
| gptkbp:encodes |
Tumor necrosis factor receptor superfamily member 18
|
| gptkbp:Entrez_Gene_ID |
8784
ENSG00000186891 |
| gptkbp:expressedIn |
gptkb:T_cells
gptkb:regulatory_T_cells |
| gptkbp:function |
regulation of T cell-mediated immune response
|
| gptkbp:geneType |
protein-coding
|
| https://www.w3.org/2000/01/rdf-schema#label |
TNFRSF18
|
| gptkbp:length |
241 amino acids
|
| gptkbp:ligand |
TNFSF18 (GITRL)
|
| gptkbp:locatedOnChromosome |
1p36.33
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:OMIM |
604437
|
| gptkbp:orthologInMouse |
Tnfrsf18
|
| gptkbp:product |
type I transmembrane protein
|
| gptkbp:regulates |
T cell activation
immune tolerance |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:target |
immunomodulatory drugs
|
| gptkbp:UniProtID |
Q9Y5U5
|
| gptkbp:bfsParent |
gptkb:CD357
gptkb:TNFRSF gptkb:GITR |
| gptkbp:bfsLayer |
8
|