|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RANK
CD265
|
|
gptkbp:associatedWith
|
gptkb:osteopetrosis
Paget disease of bone
familial expansile osteolysis
|
|
gptkbp:encodes
|
RANK protein
|
|
gptkbp:Entrez_Gene_ID
|
8792
ENSG00000141655
|
|
gptkbp:expressedIn
|
gptkb:osteoclasts
dendritic cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
tumor necrosis factor receptor superfamily member 11A
|
|
gptkbp:function
|
immune system signaling
regulation of osteoclast differentiation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0006955_(immune_response)
GO:0030216 (keratinocyte differentiation)
GO:0005034 (tumor necrosis factor-activated receptor activity)
|
|
gptkbp:HGNC_ID
|
11908
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TNFRSF11A
|
|
gptkbp:interactsWith
|
gptkb:TRAF6
TNFSF11 (RANKL)
|
|
gptkbp:length
|
616 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_18
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:mutationAssociatedWith
|
bone density disorders
|
|
gptkbp:OMIM
|
603499
|
|
gptkbp:orthologInMouse
|
Tnfrsf11a
|
|
gptkbp:UniProtID
|
O14713
|
|
gptkbp:bfsParent
|
gptkb:TNFRSF
|
|
gptkbp:bfsLayer
|
8
|