Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:A20
gptkb:TNF_alpha-induced_protein_3 |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
autoimmune diseases rheumatoid arthritis |
| gptkbp:discoveredBy |
Dixit et al.
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:encodes |
gptkb:A20_protein
|
| gptkbp:Entrez_Gene_ID |
7128
|
| gptkbp:expressedIn |
immune cells
|
| gptkbp:function |
negative regulator of inflammation
|
| https://www.w3.org/2000/01/rdf-schema#label |
TNFAIP3 gene
|
| gptkbp:locatedOnChromosome |
6q23.3
|
| gptkbp:mutationAssociatedWith |
autoinflammatory diseases
haploinsufficiency of A20 (HA20) |
| gptkbp:OMIM |
191163
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:product |
gptkb:A20
|
| gptkbp:regulates |
NF-kappaB signaling
|
| gptkbp:UniProtID |
P21580
|
| gptkbp:bfsParent |
gptkb:A20_protein
|
| gptkbp:bfsLayer |
7
|