|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:NR1A2
gptkb:THRB
gptkb:c-erbA-beta
|
|
gptkbp:associatedWith
|
gptkb:thyroid_hormone_resistance_syndrome
hearing loss
congenital hypothyroidism
|
|
gptkbp:binds
|
hormone
|
|
gptkbp:biologicalProcess
|
transcription regulation
DNA binding
hormone binding
|
|
gptkbp:encodes
|
gptkb:thyroid_hormone_receptor_beta_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000151090
7068
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
heart
liver
|
|
gptkbp:fullName
|
gptkb:thyroid_hormone_receptor_beta
|
|
gptkbp:function
|
transcription factor
nuclear receptor
|
|
gptkbp:HGNC_ID
|
11797
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
THR5
|
|
gptkbp:locatedOnChromosome
|
3
|
|
gptkbp:location
|
3p24.2
|
|
gptkbp:mutationAssociatedWith
|
gptkb:thyroid_hormone_resistance
altered metabolism
|
|
gptkbp:OMIM
|
190160
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Thrb
gptkb:rat_Thrb
gptkb:zebrafish_thrb
|
|
gptkbp:pathway
|
gptkb:thyroid_hormone_signaling_pathway
nuclear receptor transcription pathway
|
|
gptkbp:proteinFamily
|
DNA-binding domain
ligand-binding domain
nuclear receptor superfamily
|
|
gptkbp:regulates
|
development
growth
gene expression
metabolic rate
|
|
gptkbp:relatedTo
|
gptkb:thyroid_hormone_signaling_pathway
development
differentiation
metabolism regulation
|
|
gptkbp:UniProtID
|
P10828
|
|
gptkbp:bfsParent
|
gptkb:Yamaha_THR_Amplifier
|
|
gptkbp:bfsLayer
|
6
|