Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:discoveredBy |
1989
|
| gptkbp:domain |
three Kunitz-type domains
|
| gptkbp:encodedBy |
gptkb:TFPI_gene
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:placenta gptkb:testis liver |
| gptkbp:foundIn |
gptkb:human
gptkb:mouse |
| gptkbp:fullName |
Tissue Factor Pathway Inhibitor alpha
|
| gptkbp:function |
inhibits factor Xa
inhibits tissue factor (TF)-induced coagulation inhibits factor VIIa |
| https://www.w3.org/2000/01/rdf-schema#label |
TFPI-alpha
|
| gptkbp:inhibitedBy |
extrinsic coagulation pathway
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_2q32
|
| gptkbp:location |
gptkb:plasma
platelets endothelial cells |
| gptkbp:molecularWeight |
~34 kDa
|
| gptkbp:postTranslationalModification |
glycosylation
|
| gptkbp:relatedTo |
gptkb:TFPI-beta
|
| gptkbp:UniProtID |
P10646-1
|
| gptkbp:bfsParent |
gptkb:tissue_factor_pathway_inhibitor
|
| gptkbp:bfsLayer |
7
|