T-cell surface glycoprotein CD5

URI: https://gptkb.org/entity/T-cell_surface_glycoprotein_CD5
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName T1
CD5 antigen
Leu-1
gptkbp:domain SRCR domain
gptkbp:encodedBy CD5 gene
gptkbp:Entrez_Gene_ID 921
gptkbp:expressedIn thymocytes
peripheral T cells
subset of B cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function regulation of immune response
negative regulation of T-cell receptor signaling
gptkbp:HGNC_ID CD5
https://www.w3.org/2000/01/rdf-schema#label T-cell surface glycoprotein CD5
gptkbp:interactsWith gptkb:LCK
gptkb:PTPN6
gptkb:GRB2
gptkb:CD72
gptkbp:locatedOn T cell surface
B cell surface
gptkbp:locatedOnChromosome gptkb:chromosome_11q12.2
gptkbp:molecularWeight 67 kDa
gptkbp:OMIM 186490
gptkbp:postTranslationalModification phosphorylation
glycosylation
gptkbp:significance marker for T-cell lymphomas
marker for chronic lymphocytic leukemia
gptkbp:structure single-pass type I membrane protein
gptkbp:subcellularLocation gptkb:plasma_membrane
gptkbp:UniProtID P06127
gptkbp:bfsParent gptkb:T5C5
gptkbp:bfsLayer 8