T-cell large granular lymphocytic leukemia

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
lymphoproliferative disorder
gptkbp:affects gptkb:T-cells
blood
gptkbp:associatedWith gptkb:STAT3_mutation
gptkb:STAT5b_mutation
rheumatoid arthritis
gptkbp:diagnosedBy bone marrow biopsy
blood smear
flow cytometry
gptkbp:firstDescribed 1977
gptkbp:hasMedianAgeOfOnset 60 years
gptkbp:hasSexRatio slight male predominance
https://www.w3.org/2000/01/rdf-schema#label T-cell large granular lymphocytic leukemia
gptkbp:ICD-10_code C91.7
gptkbp:prevalence rare
gptkbp:prognosis chronic
indolent
gptkbp:subclassOf large granular lymphocytic leukemia
gptkbp:symptom gptkb:anemia
autoimmune disorders
fatigue
splenomegaly
neutropenia
recurrent infections
gptkbp:treatment gptkb:cyclophosphamide
gptkb:cyclosporine
gptkb:prednisone
gptkb:methotrexate
immunosuppressive therapy
gptkbp:bfsParent gptkb:Large_Granular_Lymphocytic_Leukemia
gptkbp:bfsLayer 8