Large Granular Lymphocytic Leukemia
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
leukemia lymphoproliferative disorder |
| gptkbp:affects |
gptkb:natural_killer_cells
gptkb:T-cells large granular lymphocytes |
| gptkbp:associatedWith |
autoimmune disorders
rheumatoid arthritis |
| gptkbp:diagnosedBy |
bone marrow biopsy
blood smear flow cytometry |
| gptkbp:firstDescribed |
1985
|
| gptkbp:gender |
slightly more common in males
|
| https://www.w3.org/2000/01/rdf-schema#label |
Large Granular Lymphocytic Leukemia
|
| gptkbp:ICD-10_code |
gptkb:C91.8
|
| gptkbp:medianAge |
60 years
|
| gptkbp:mutationAssociatedWith |
gptkb:STAT3_mutation
gptkb:STAT5b_mutation |
| gptkbp:prevalence |
rare
|
| gptkbp:prognosis |
chronic disease
indolent course |
| gptkbp:subspecies |
gptkb:T-cell_large_granular_lymphocytic_leukemia
gptkb:chronic_NK-cell_lymphocytosis |
| gptkbp:symptom |
gptkb:anemia
splenomegaly neutropenia recurrent infections |
| gptkbp:treatment |
gptkb:cyclophosphamide
gptkb:cyclosporine gptkb:methotrexate immunosuppressive therapy |
| gptkbp:bfsParent |
gptkb:LGL_Leukemia
|
| gptkbp:bfsLayer |
7
|