Statements (38)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:leukemia
gptkb:disease |
| gptkbp:affects |
adults
children T lymphocytes |
| gptkbp:diagnosedBy |
gptkb:blood_test
bone marrow biopsy immunophenotyping |
| gptkbp:firstDescribed |
1970s
|
| gptkbp:fullName |
gptkb:T-cell_acute_lymphoblastic_leukemia
|
| gptkbp:ICD-10_code |
gptkb:C91.0
|
| gptkbp:incidence |
15-25% of childhood ALL cases
25% of adult ALL cases |
| gptkbp:marking |
gptkb:TdT
gptkb:CD3 gptkb:CD7 CD2 CD5 |
| gptkbp:mutationAssociatedWith |
gptkb:NOTCH1_mutation
CDKN2A deletion TAL1 rearrangement |
| gptkbp:prognosis |
variable
|
| gptkbp:relapseRate |
higher than B-ALL
|
| gptkbp:riskFactor |
gptkb:Down_syndrome
radiation exposure genetic mutations |
| gptkbp:subspecies |
gptkb:leukemia
|
| gptkbp:symptom |
fever
fatigue bone pain easy bruising enlarged lymph nodes |
| gptkbp:treatment |
gptkb:targeted_therapy
chemotherapy stem cell transplant |
| gptkbp:bfsParent |
gptkb:T-cell_acute_lymphoblastic_leukemia
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
T-ALL
|