Superoxide dismutase [Cu-Zn]

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:alternativeName	gptkb:SOD1 CuZnSOD superoxide:superoxide oxidoreductase
gptkbp:associatedWith	amyotrophic lateral sclerosis
gptkbp:biologicalProcess	antioxidant activity superoxide dismutase activity
gptkbp:catalyzes	dismutation of superoxide radicals
gptkbp:cofactor	copper zinc
gptkbp:discoveredBy	gptkb:Irwin_Fridovich
gptkbp:discoveredIn	1969
gptkbp:EC_number	1.15.1.1
gptkbp:foundIn	gptkb:cytoplasm extracellular space
gptkbp:function	protects cells from oxidative damage
gptkbp:gene	gptkb:SOD1
gptkbp:gene_symbol_(bovine)	gptkb:SOD1
gptkbp:heldBy	metalloenzyme
gptkbp:locatedOnChromosome	gptkb:21q22.11
gptkbp:location	cytosol mitochondria (in some species)
gptkbp:molecularWeight	~16 kDa per subunit
gptkbp:mutationAssociatedWith	linked to familial ALS
gptkbp:OMIM	147450
gptkbp:organism	gptkb:Bos_taurus gptkb:Homo_sapiens
gptkbp:PDB	1CBJ
gptkbp:product	hydrogen peroxide oxygen
gptkbp:proteinFamily	gptkb:superoxide_dismutase_family
gptkbp:substrate	gptkb:superoxide_anion
gptkbp:subunit	homodimer
gptkbp:UniProtID	gptkb:P00441
gptkbp:bfsParent	gptkb:SOD1_protein
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	Superoxide dismutase [Cu-Zn]