|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:antibiotic
sulfonamide
|
|
gptkbp:affects
|
gptkb:Stevens-Johnson_syndrome
gptkb:anemia
allergic reactions
crystalluria
|
|
gptkbp:ATCCode
|
J01EB06
|
|
gptkbp:became_widely_used_after
|
1935
|
|
gptkbp:CASNumber
|
63-74-1
|
|
gptkbp:chemicalFormula
|
C6H8N2O2S
|
|
gptkbp:discoveredBy
|
1935
|
|
gptkbp:Elixir_Sulfanilamide_disaster_led_to
|
1938 Federal Food, Drug, and Cosmetic Act
|
|
gptkbp:firstSynthesized
|
1908
Paul Gelmo
|
|
gptkbp:has_hazard
|
toxic if ingested in large amounts
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sulfanilamide
|
|
gptkbp:involvedIn
|
gptkb:Elixir_Sulfanilamide_disaster
|
|
gptkbp:IUPACName
|
gptkb:4-aminobenzenesulfonamide
|
|
gptkbp:mechanismOfAction
|
inhibits dihydropteroate synthase
|
|
gptkbp:meltingPoint
|
164 °C
|
|
gptkbp:metabolism
|
gptkb:Prontosil
|
|
gptkbp:molecularWeight
|
172.20 g/mol
|
|
gptkbp:pKa
|
10.4
|
|
gptkbp:PubChem_CID
|
5333
|
|
gptkbp:relatedTo
|
sulfa drugs
|
|
gptkbp:solubility
|
slightly soluble
|
|
gptkbp:synonym
|
gptkb:4-aminobenzenesulfonamide
p-aminobenzenesulfonamide
para-aminobenzenesulfonamide
|
|
gptkbp:usedFor
|
bacterial infections
antibacterial drug
|
|
gptkbp:was_the_basis_for
|
gptkb:Prontosil
|
|
gptkbp:bfsParent
|
gptkb:SD2
|
|
gptkbp:bfsLayer
|
5
|