Stevens-Johnson syndrome

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:disease
medical emergency
gptkbp:affects gptkb:skin
mucous membranes
gptkbp:ageGroupAffected all ages
gptkbp:alsoKnownAs gptkb:SJS
gptkbp:cause unknown
infection
adverse drug reaction
gptkbp:commonDrugsCausing gptkb:NSAIDs
antibiotics
allopurinol
anticonvulsants
gptkbp:commonIn adults
males
gptkbp:complication gptkb:pneumonia
sepsis
vision loss
organ failure
permanent skin damage
gptkbp:diagnosedBy clinical evaluation
skin biopsy
gptkbp:field immunology
internal medicine
dermatology
gptkbp:firstDescribed 1922
https://www.w3.org/2000/01/rdf-schema#label Stevens-Johnson syndrome
gptkbp:ICD-10_code L51.1
gptkbp:mortalityRate 5-10%
gptkbp:namedAfter gptkb:Albert_Mason_Stevens
gptkb:Frank_Chambliss_Johnson
gptkbp:relatedTo gptkb:toxic_epidermal_necrolysis
gptkbp:riskFactor immunosuppression
HIV infection
genetic predisposition
gptkbp:symptom fever
fatigue
sore throat
blisters
painful red or purplish rash
skin peeling
gptkbp:treatment supportive care
pain management
wound care
hospitalization
IV fluids
antibiotics (if infection present)
discontinuation of causative drug
gptkbp:bfsParent gptkb:SJS
gptkb:phenytoin
gptkb:fluconazole
gptkb:Sulfanilamide
gptkb:carbamazepine
gptkb:Sulfonamides
gptkbp:bfsLayer 6