Stevens-Johnson syndrome

GPTKB entity

Properties (43)
Predicate Object
gptkbp:instanceOf medical condition
gptkbp:associatedWith antibiotics
certain medications
non-steroidal anti-inflammatory drugs (NSAIDs)
anti-seizure medications
gptkbp:causedBy medications
vaccines
infections
gptkbp:diseaseResistance clinical evaluation
more common in adults
skin biopsy
rare condition
affects all ages
can lead to long-term complications
depends on prompt treatment
higher mortality rate in older adults
gptkbp:historicalContext first described in 1922
increased recognition in the late 20th century
named after two dermatologists
https://www.w3.org/2000/01/rdf-schema#label Stevens-Johnson syndrome
gptkbp:impact supportive care
corticosteroids
immunosuppressive agents
gptkbp:inheritsFrom can occur within days to weeks
gptkbp:public_perception educational campaigns exist
important for early recognition
healthcare_provider_training_is_essential
gptkbp:relatedPatent vision problems
sepsis
permanent skin damage
toxic epidermal necrolysis
gptkbp:research investigations into new treatments
ongoing studies on genetic factors
studies on drug safety
gptkbp:riskManagement genetic predisposition
HIV infection
previous drug reactions
gptkbp:safetyFeatures genetic testing
avoid known triggers
gptkbp:symptoms blistering
skin rash
mucous membrane involvement
gptkbp:threats can be life-threatening