Squamous Cell Carcinoma of the Lung

URI: https://gptkb.org/entity/Squamous_Cell_Carcinoma_of_the_Lung
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:accountsFor 20-30% of Lung Cancers
gptkbp:associatedWith Cavitating Lung Mass
Pancoast Tumor
gptkbp:canMetastasizeTo gptkb:Brain
gptkb:Lymph_Nodes
gptkb:Bones
Liver
gptkbp:cause Atelectasis
Obstructive Pneumonia
gptkbp:commonIn Males
Older Adults
gptkbp:diagnosedBy gptkb:Bronchoscopy
Biopsy
CT Scan
gptkbp:firstDescribed 1912
gptkbp:histology Intercellular Bridges
Keratin Pearls
https://www.w3.org/2000/01/rdf-schema#label Squamous Cell Carcinoma of the Lung
gptkbp:ICD-10_code C34
gptkbp:location Central Lung
gptkbp:marking gptkb:p63
p40
CK5/6
gptkbp:mutationAssociatedWith gptkb:PIK3CA
gptkb:CDKN2A
gptkb:TP53
gptkbp:originatedIn Bronchial Epithelium
gptkbp:paraneoplasticSyndrome gptkb:Hypercalcemia
gptkbp:prognosis Generally Poor
gptkbp:rarelyHas ALK Rearrangement
EGFR Mutation
ROS1 Rearrangement
gptkbp:riskFactor gptkb:Chronic_Obstructive_Pulmonary_Disease
Exposure to Asbestos
Tobacco Smoking
gptkbp:stagedBy TNM System
gptkbp:subspecies gptkb:Non-Small_Cell_Lung_Cancer
Keratinizing Squamous Cell Carcinoma
Non-keratinizing Squamous Cell Carcinoma
gptkbp:symptom gptkb:Dyspnea
Cough
Chest Pain
Hemoptysis
gptkbp:treatment Radiation Therapy
Surgery
Chemotherapy
gptkbp:bfsParent gptkb:cancer
gptkbp:bfsLayer 4