|
gptkbp:instanceOf
|
peptide
|
|
gptkbp:alternativeName
|
somatotropin release-inhibiting factor
growth hormone-inhibiting hormone
|
|
gptkbp:CASNumber
|
38916-34-6
|
|
gptkbp:degradedBy
|
somatostatinase
|
|
gptkbp:discoveredBy
|
gptkb:Brazeau_et_al.
|
|
gptkbp:discoveredIn
|
1973
|
|
gptkbp:foundIn
|
central nervous system
pancreas
gastrointestinal system
|
|
gptkbp:gene
|
SST
|
|
gptkbp:halfLife
|
1–3 minutes
|
|
gptkbp:hasApprovedDrug
|
no
|
|
gptkbp:hasIsoform
|
gptkb:somatostatin-14
gptkb:somatostatin-28
|
|
gptkbp:hasMolecularFormula
|
C76H104N18O19S2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Somatostatin
|
|
gptkbp:inhibitedBy
|
cell proliferation
insulin secretion
glucagon secretion
growth hormone secretion
intestinal motility
exocrine secretion
gastrin secretion
thyroid-stimulating hormone secretion
|
|
gptkbp:KEGGID
|
D08465
|
|
gptkbp:MeSH_ID
|
D012765
|
|
gptkbp:molecularWeight
|
1637.9 Da
|
|
gptkbp:predecessor
|
gptkb:preprosomatostatin
|
|
gptkbp:producedBy
|
gptkb:pancreatic_delta_cells
gastrointestinal tract
hypothalamus
|
|
gptkbp:PubChem_CID
|
16129688
CHEBI:27645
|
|
gptkbp:recipient
|
gptkb:SSTR1
gptkb:SSTR2
gptkb:SSTR3
gptkb:SSTR4
gptkb:SSTR5
|
|
gptkbp:regulates
|
endocrine system
neurotransmission
exocrine system
|
|
gptkbp:syntheticAnalog
|
gptkb:octreotide
gptkb:lanreotide
gptkb:pasireotide
|
|
gptkbp:UNII
|
6Z5B6HVF6O
|
|
gptkbp:usedAs
|
diagnostic agent
therapeutic agent
|
|
gptkbp:bfsParent
|
gptkb:Glucagon
|
|
gptkbp:bfsLayer
|
6
|