|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:encodedBy
|
SSTR5 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000114054
|
|
gptkbp:family
|
somatostatin receptor family
|
|
gptkbp:fullName
|
Somatostatin receptor type 5
|
|
gptkbp:function
|
G-protein coupled receptor for somatostatin
Inhibits adenylyl cyclase
Mediates somatostatin effects in endocrine signaling
|
|
gptkbp:gene
|
gptkb:SSTR5
|
|
gptkbp:HGNC_ID
|
11331
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SSTR5
|
|
gptkbp:interactsWith
|
gptkb:G_proteins
|
|
gptkbp:length
|
364
|
|
gptkbp:ligand
|
gptkb:somatostatin
|
|
gptkbp:locatedOnChromosome
|
16p13.3
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:modulatedBy
|
cell proliferation
hormone secretion
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:OMIM
|
182456
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:RefSeq
|
NM_001053
|
|
gptkbp:significance
|
implicated in pituitary adenomas
target for somatostatin analog drugs
|
|
gptkbp:structure
|
7 transmembrane domains
|
|
gptkbp:tissue_specificity
|
gptkb:pituitary_gland
brain
gastrointestinal tract
pancreas
|
|
gptkbp:UniProtID
|
P48357
|
|
gptkbp:bfsParent
|
gptkb:somatostatin
gptkb:chromosome_16p13.3
gptkb:Somatostatin
|
|
gptkbp:bfsLayer
|
7
|