|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD328
|
|
gptkbp:associatedWith
|
immune evasion by tumors
|
|
gptkbp:contains
|
ITIM motif
|
|
gptkbp:encodedBy
|
gptkb:SIGLEC7_gene
|
|
gptkbp:Entrez_Gene_ID
|
27036
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
monocytes
some T cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
immune regulation
sialic acid-binding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Siglec-7
|
|
gptkbp:inhibitoryReceptor
|
true
|
|
gptkbp:interactsWith
|
sialylated glycans
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19q13.4
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:memberOf
|
gptkb:immunoglobulin_superfamily
gptkb:Siglec_family
|
|
gptkbp:modulatedBy
|
inflammatory responses
|
|
gptkbp:OMIM
|
604405
|
|
gptkbp:PDB
|
1O7S
|
|
gptkbp:regulates
|
immune cell activation
NK cell cytotoxicity
|
|
gptkbp:structure
|
contains immunoglobulin-like domains
|
|
gptkbp:UniProtID
|
gptkb:Q9Y286
|
|
gptkbp:bfsParent
|
gptkb:sialic_acid-binding_immunoglobulin-like_lectins_(Siglecs)
gptkb:CD328
gptkb:CD330
gptkb:Siglec_family
|
|
gptkbp:bfsLayer
|
8
|