Statements (61)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Genetics
|
| gptkbp:advocacy |
important for policy changes
|
| gptkbp:affects |
red blood cells
|
| gptkbp:associated_with |
fatigue
jaundice mental health challenges vision problems chronic pain syndrome increased risk of infections gallstones increased risk of blood clots leg ulcers delayed growth in children painful episodes sickle-shaped red blood cells |
| gptkbp:caused_by |
mutation in the HBB gene
|
| gptkbp:clinical_trial |
ongoing for new therapies
|
| gptkbp:collaboration |
for research and treatment advancements
|
| gptkbp:community_health |
in many countries
requires lifelong management |
| gptkbp:community_impact |
affects millions worldwide
|
| gptkbp:community_involvement |
important for early diagnosis and treatment.
|
| gptkbp:community_support |
crucial for patients and families
|
| gptkbp:complication |
stroke
pulmonary hypertension organ damage acute chest syndrome |
| gptkbp:cultural_impact |
in affected communities
|
| gptkbp:diagnosis |
hemoglobin electrophoresis
|
| gptkbp:economic_policy |
aims to improve healthcare access
|
| gptkbp:educational_resources |
available for patients and families
|
| gptkbp:first_described_by |
in the early 20th century
|
| gptkbp:genetic_diversity |
in populations with malaria resistance
|
| gptkbp:genetic_studies |
recommended for affected families
|
| gptkbp:historical_context |
linked to slavery and migration patterns
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sickle Cell Disease
|
| gptkbp:inherits_from |
autosomal recessive
|
| gptkbp:is_involved_in |
gptkb:Sickle_Cell_Society
gptkb:Sickle_Cell_Disease_Association_of_America gptkb:Sickle_Cell_Foundation provide resources and networking |
| gptkbp:lifespan |
reduced compared to general population
|
| gptkbp:patient_education |
important for management
|
| gptkbp:prevalence |
more common in African descent
more common in Mediterranean descent more common in Middle Eastern descent |
| gptkbp:public_awareness |
aim to educate about the disease
|
| gptkbp:research_focus |
gptkb:gene_therapy
new medications pain management strategies |
| gptkbp:research_institutes |
focused on treatment advancements
|
| gptkbp:screenings |
newborn screening programs
|
| gptkbp:symptoms |
gptkb:anemia
frequent infections pain crises swelling in hands and feet |
| gptkbp:treatment |
bone marrow transplant
hydroxyurea blood transfusions |
| gptkbp:bfsParent |
gptkb:SGMO
|
| gptkbp:bfsLayer |
5
|