|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
5
|
|
gptkbp:bfsParent
|
gptkb:Ciba-Geigy
gptkb:Searle_Pharmaceuticals
|
|
gptkbp:activities
|
gptkb:selective_serotonin_reuptake_inhibitor_(SSRI)
|
|
gptkbp:appointed_by
|
oral tablet
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Zoloft
gptkb:Sertralin
Lustral
Serlain
|
|
gptkbp:clinical_trial
|
Phase IV
Phase III
|
|
gptkbp:contraindication
|
MAO inhibitors
hypersensitivity to sertraline
|
|
gptkbp:discovered_by
|
gptkb:Pfizer
|
|
gptkbp:dosage_form
|
100 mg daily
50 mg daily
|
|
gptkbp:duration
|
several weeks
long-term use possible
|
|
gptkbp:effective_date
|
gptkb:1991
|
|
gptkbp:formulation
|
gptkb:tablet
liquid solution
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sertraline
|
|
gptkbp:ingredients
|
C17 H17 Cl2 N
|
|
gptkbp:interacts_with
|
gptkb:warfarin
NSAI Ds
other SSR Is
|
|
gptkbp:is_available_on
|
generic drug
|
|
gptkbp:is_used_for
|
gptkb:historical_event
gptkb:post-traumatic_stress_disorder
anxiety disorders
obsessive-compulsive disorder
panic disorder
|
|
gptkbp:lifespan
|
24 hours
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:requires
|
available online
|
|
gptkbp:side_effect
|
dizziness
fatigue
nausea
insomnia
dry mouth
weight gain
sexual dysfunction
bleeding risk
serotonin syndrome
hyponatremia
|
|
gptkbp:suitable_for
|
pregnant women
children under 18
breastfeeding women
people with kidney disease
people with liver disease
|
|
gptkbp:symptoms
|
dizziness
nausea
sleep disturbances
irritability
|
|
gptkbp:type_of
|
79617-96-2
|