Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:activatedBy |
gptkb:interleukin-12
gptkb:interleukin-23 |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
autoimmune diseases rheumatoid arthritis inflammatory bowel disease |
| gptkbp:encodes |
Signal transducer and activator of transcription 4
|
| gptkbp:Entrez_Gene_ID |
6775
ENSG00000138378 |
| gptkbp:expressedIn |
immune cells
|
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
11363
|
| https://www.w3.org/2000/01/rdf-schema#label |
STAT4 gene
|
| gptkbp:involvedIn |
immune response
cytokine signaling |
| gptkbp:locatedOnChromosome |
chromosome 2
2q32.2-q32.3 |
| gptkbp:mutationAssociatedWith |
altered immune response
|
| gptkbp:OMIM |
600558
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Stat4
|
| gptkbp:product |
STAT4 protein
|
| gptkbp:regulates |
Th1 cell differentiation
interferon-gamma production |
| gptkbp:UniProtID |
Q14765
|
| gptkbp:bfsParent |
gptkb:STAT4
|
| gptkbp:bfsLayer |
8
|