Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
proteolytic cleavage
|
| gptkbp:alternativeSplicing |
gptkb:SREBP-1c
gptkb:SREBP-2 |
| gptkbp:domain |
basic helix-loop-helix leucine zipper
|
| gptkbp:encodedBy |
gptkb:SREBF1_gene
|
| gptkbp:fullName |
Sterol regulatory element-binding protein 1a
|
| gptkbp:function |
transcription factor
|
| gptkbp:GO_term |
gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated)
GO:0045893 (positive regulation of transcription, DNA-templated) |
| https://www.w3.org/2000/01/rdf-schema#label |
SREBP-1a
|
| gptkbp:interactsWith |
gptkb:SCAP
Insig |
| gptkbp:locale |
gptkb:endoplasmic_reticulum
gptkb:nucleus |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:regulates |
gptkb:LDLR_gene
cholesterol homeostasis lipid biosynthesis fatty acid metabolism ACACA gene FASN gene HMGCR gene |
| gptkbp:species |
gptkb:human
gptkb:mouse |
| gptkbp:UniProtID |
P36956-1
|
| gptkbp:bfsParent |
gptkb:SREBP-1c
|
| gptkbp:bfsLayer |
7
|