SPARC protein

GPTKB entity

Statements (62)
Predicate Object
gptkbp:instanceOf protein
gptkbp:associatedWith wound healing
cell adhesion
tumor progression
gptkbp:diedIn inflammation
gptkbp:function extracellular matrix regulation
https://www.w3.org/2000/01/rdf-schema#label SPARC protein
gptkbp:influences matrix metalloproteinases
gptkbp:interactsWith collagen
fibronectin
gptkbp:involvedIn angiogenesis
gptkbp:is_evaluated_by various tissues
gptkbp:isAssociatedWith diabetes
autoimmune diseases
neuroplasticity
cardiovascular diseases
chronic kidney disease
cancer metastasis
gptkbp:isAttendedBy fibroblasts
gptkbp:isFoundIn extracellular space
gptkbp:isInvolvedIn cell differentiation
cellular homeostasis
cellular stress response
immune response
neurodegenerative diseases
neuroinflammation
fibrosis
cell signaling pathways
cell survival
cellular aging
atherosclerosis
chronic inflammation
tissue repair
pulmonary diseases
bone remodeling
cancer therapy response
cell-matrix interactions
metastatic spread
neoplastic processes
gptkbp:isKnownFor integrins
gptkbp:isLinkedTo age-related diseases
liver diseases
metabolic disorders
chronic pain
angiogenic factors
chronic_stress
gptkbp:isLocatedIn brain
muscle tissue
placenta
lungs
skin
adipose tissue
embryogenesis
tumor microenvironment
gastrointestinal tract
gptkbp:isRegulatedBy transforming growth factor beta (TGF-β)
gptkbp:isStudiedIn cancer research
regenerative medicine
therapeutic targets
biomarker potential
gptkbp:regulates cell proliferation
cell migration