Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:affects |
immune response
|
| gptkbp:associated_with |
fibrosis
cell adhesion |
| gptkbp:code |
SPARC gene
|
| gptkbp:community |
cell migration
|
| gptkbp:function |
extracellular matrix regulation
|
| gptkbp:has_influence_on |
tumor angiogenesis
|
| gptkbp:has_role |
inflammation
|
| gptkbp:has_website |
EF-hand domain
FAS1 domain |
| https://www.w3.org/2000/01/rdf-schema#label |
SPARC protein
|
| gptkbp:influences |
cell proliferation
|
| gptkbp:interacts_with |
gptkb:Collage
|
| gptkbp:involved_in |
wound healing
tissue repair bone remodeling |
| gptkbp:is_associated_with |
metabolic disorders
chronic diseases chronic inflammation tumor microenvironment interactions |
| gptkbp:is_expressed_in |
muscle tissue
various tissues adipose tissue cancer cells endothelial cells normal tissues |
| gptkbp:is_found_in |
extracellular space
|
| gptkbp:is_involved_in |
cell signaling pathways
tumor suppression tumor microenvironment neovascularization cellular responses to stress neoplastic processes cellular migration processes |
| gptkbp:is_known_for |
modulating cell-matrix interactions
its role in ECM remodeling |
| gptkbp:is_known_to |
influence ECM composition
modulate immune cell function |
| gptkbp:is_linked_to |
metastasis
cellular signaling pathways angiogenic factors cellular stress responses cellular adhesion molecules |
| gptkbp:is_part_of |
extracellular matrix
cellular microenvironment |
| gptkbp:is_regulated_by |
gptkb:TGF-beta
hypoxia |
| gptkbp:is_studied_for |
therapeutic potential
its role in cancer therapy |
| gptkbp:is_studied_in |
cancer research
biomarker research |
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:may_regulate |
cell differentiation
|
| gptkbp:produced_by |
fibroblasts
|
| gptkbp:regulates |
gptkb:matrix_metalloproteinases
angiogenesis |
| gptkbp:role |
tumor progression
|
| gptkbp:bfsParent |
gptkb:SPARC_family
|
| gptkbp:bfsLayer |
7
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